- Academic Editor
-
-
-
†These authors contributed equally.
Background: This study aimed to investigate the relationship between
coronavirus disease 2019 (COVID-19) disease and maternal and neonatal outcomes.
Methods: This is a retrospective cohort study. This study analyzed 3615
participants from Fujian Provincial Maternity and Child Health Hospital Fujian
Obstetrics and Gynecology Hospital from November 1, 2022, to January 31, 2023.
All pregnant women must provide a 24-hour nucleic acid test report when they are
admitted to the hospital to deliver babies. Chi-square test and linear regression
analyses were used to evaluate the risk of COVID-19 infection with the maternal
outcome and neonatal outcomes. Results: Finally, 3615 patients were
included in the cohort study. 549 (15.2%) were diagnosed with COVID-19
infection. The most common symptom is fever, cough, sore throat. 51 (9.2%)
newborns had positive test results. In addition, the mother with COVID-19
infection were significantly associated with a higher rate of premature rupture
of membranes (PPROM) and postpartum hemorrhage. Furthermore, a mother with
COVID-19 infection was significantly associated with a higher rate of low birth
weight infant (LBW) and macrosomia in newborns, higher rate of respiratory
distress syndrome (RDS), higher rate of intro-ventricular hemorrhage (IVH),
higher rate of neonatal pneumonia, and a higher rate of aspiration of amniotic
fluid and meconium syndrome (AAFMS) (all p